A high-quality library (MOURA library) consisting of 1011 diverse and functional clones, constructed by original gene amplification technology.
Covers a wide repertoire of antibodies, including autoantibodies, using pre-B cells from bone marrow and spleen.
Our ideas and technologies have enabled efficient screening and isolation of phage antibodies against cell membrane antigens.
A high-quality phage display antibody library with functionality and completeness covering the entire antibody gene of 1011 repertoires
hMOURA subset libraries (<106 size) after narrowing down against cell-surface antigens on 50 kinds of cancer cells. Enables efficient isolation of desired mAbs.
Single domain antibody library with the world’s largest diversity (1011 size), functionality and completeness
Derived from our human antibody library. A canine antibody library with the world’s largest diversity (1010 size), functionality and completeness.
Derived from our human antibody library. A feline antibody library (1010 size) with functionality and completeness.
Single domain antibody library with the world’s largest diversity (1011 size), functionality and completeness.
*"MOURA" means "comprehensiveness" in Japanese.
In tumor-bearing mice, it showed a stronger tumor growth inhibitory effect than Cetuximab. 1
Anti-TfR antibody that currently has the strongest anti-cancer effect in the world (preparing to start human trials at other companies) 2, 3
World’s first anti-ITG A6B4 complex antibody 4
World’s first anti-CADM1 / IgSF4 human antibody 5, 6, 7
Co-administration of the integrin antibody enhances the effect of the anticancer drug and almost eliminates the tumor.
*These antibodies were acquired by academic efforts by Drs. Morishita and Kurosawa using our technologies before MabGenesis was founded.