Collaborative Antibody Discovery

We are looking for partners who are interested in collaborative antibody discovery to identify innovative monoclonal antibody therapeutics. By taking best advantage of MOURA libraries and efficient monoclonal antibody isolation technology IMPACT, MabGenesis delivers quality monoclonal antibodies against targets of interest to partners.

Collaboration with MabGenesis in Antibody Discovery

*Single chain variable fragment

How Our Screening Works

STEP 1
Screening/Panning

  • Several rounds of panning with cells or immobilized antigens
  • Isolate antibodies that meet the criteria

Screening/Panning
STEP 2
Identifying Target Phage Antibodies

  • Evaluate the functionality of target phage antibodies
  • Gene sequencing of target phage antibodies

Identifying Target Phage Antibodies
STEP 3
IgG Conversion & Expression

  • Convert scFv or scVHH to IgG
  • Expression and purification of IgG antibodies

IgG Conversion & Expression
STEP 4
IgG Functional Evaluation

  • FACS binding evaluation
  • Binding kinetics evaluation
  • Cell level function evaluation

IgG Functional Evaluation